Studies on Abnormality of Glucose Tolerance in Subjects with Liver Cirrhosis

Clinical investigation on glucose tolerance in liver cirrhosis.

Forty-six patients with liver cirrhosis were classified into three groups according to glucose tolerance test and the presence or absence of diabetic state. The results of xylitol tolerance test, galactose tolerance test, BSP retention, ICG disappearance rate and other routine liver function tests were compared between these three groups. The results show that liver cirrhosis in patients with o...

MR Quantification of Total Liver Fat in Patients with Impaired Glucose Tolerance and Healthy Subjects

OBJECTIVE To explore the correlations between liver fat content and clinical index in patients with impaired glucose tolerance (IGT) and healthy subjects. MATERIALS AND METHODS 56 subjects were enrolled and each of them underwent upper-abdominal MRI examination that involved a T1 VIBE Dixon sequence. 14 was clinically diagnosed with IGT (collectively as IGT group ) while 42 showed normal gluc...

Electrolyte studies on patients with cirrhosis of the liver.

Effects of glucose and meal ingestion on incretin secretion in Japanese subjects with normal glucose tolerance

UNLABELLED Aims/Introduction:  Gastric inhibitory polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) are the major incretins; their secretion after various nutrient loads are well-evaluated in Caucasians. However, little is known of the relationship between incretin secretion and differing nutritional loading in Japanese subjects. In the present study, we evaluated GIP and GLP-1 secretion in...

Identification of insulin resistance in subjects with normal glucose tolerance.

INTRODUCTION Decreased insulin action (insulin resistance) is crucial in the pathogenesis of type 2 diabetes. Decreased insulin action can even be found in normoglycaemic patients, and they still bear increased risks for cardiovascular disease. In this study, we built models using data from metabolic syndrome (Mets) components and the oral glucose tolerance test (OGTT) to detect insulin resista...